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The Effect of Dimethyl Sulfoxide on Supercoiled DNA Relaxation Catalyzed by Type I Topoisomerases

The effects of dimethyl sulfoxide (DMSO) on supercoiled plasmid DNA relaxation catalyzed by two typical type I topoisomerases were investigated in our studies. It is shown that DMSO in a low concentration (less than 20%, v/v) can induce a dose-related enhancement of the relaxation efficiency of Esch...

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Detalles Bibliográficos
Autores principales: Lv, Bei, Dai, Yunjia, Liu, Ju, Zhuge, Qiang, Li, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670693/
https://www.ncbi.nlm.nih.gov/pubmed/26682217
http://dx.doi.org/10.1155/2015/320490