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DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E(2) Growth Factor Release in Response to Low and High LET Ionizing Radiation
Common cancer therapies employ chemicals or radiation that damage DNA. Cancer and normal cells respond to DNA damage by activating complex networks of DNA damage sensor, signal transducer, and effector proteins that arrest cell cycle progression, and repair damaged DNA. If damage is severe enough, t...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670845/ https://www.ncbi.nlm.nih.gov/pubmed/26697402 http://dx.doi.org/10.3389/fonc.2015.00260 |