High-Dose Estradiol-Replacement Therapy Enhances the Renal Vascular Response to Angiotensin II via an AT(2)-Receptor Dependent Mechanism

Physiological levels of estrogen appear to enhance angiotensin type 2 receptor- (AT(2)R-) mediated vasodilatation. However, the effects of supraphysiological levels of estrogen, analogous to those achieved with high-dose estrogen replacement therapy in postmenopausal women, remain unknown. Therefore...

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Detalles Bibliográficos
Autores principales: Safari, Tahereh, Nematbakhsh, Mehdi, Evans, Roger G., Denton, Kate M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670851/
https://www.ncbi.nlm.nih.gov/pubmed/26681937
http://dx.doi.org/10.1155/2015/682745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670851/
https://www.ncbi.nlm.nih.gov/pubmed/26681937
http://dx.doi.org/10.1155/2015/682745

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