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High-Dose Estradiol-Replacement Therapy Enhances the Renal Vascular Response to Angiotensin II via an AT(2)-Receptor Dependent Mechanism
Physiological levels of estrogen appear to enhance angiotensin type 2 receptor- (AT(2)R-) mediated vasodilatation. However, the effects of supraphysiological levels of estrogen, analogous to those achieved with high-dose estrogen replacement therapy in postmenopausal women, remain unknown. Therefore...
Autores principales: | Safari, Tahereh, Nematbakhsh, Mehdi, Evans, Roger G., Denton, Kate M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670851/ https://www.ncbi.nlm.nih.gov/pubmed/26681937 http://dx.doi.org/10.1155/2015/682745 |
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