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Yokukansan Increases 5-HT(1A) Receptors in the Prefrontal Cortex and Enhances 5-HT(1A) Receptor Agonist-Induced Behavioral Responses in Socially Isolated Mice

The traditional Japanese medicine yokukansan has an anxiolytic effect, which occurs after repeated administration. In this study, to investigate the underlying mechanisms, we examined the effects of repeated yokukansan administration on serotonin 1A (5-HT(1A)) receptor density and affinity and its e...

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Detalles Bibliográficos
Autores principales: Ueki, Toshiyuki, Mizoguchi, Kazushige, Yamaguchi, Takuji, Nishi, Akinori, Ikarashi, Yasushi, Hattori, Tomohisa, Kase, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670863/
https://www.ncbi.nlm.nih.gov/pubmed/26681968
http://dx.doi.org/10.1155/2015/726471