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Adenoviral Vector Vaccination Induces a Conserved Program of CD8(+) T Cell Memory Differentiation in Mouse and Man

Following exposure to vaccines, antigen-specific CD8(+) T cell responses develop as long-term memory pools. Vaccine strategies based on adenoviral vectors, e.g., those developed for HCV, are able to induce and sustain substantial CD8(+) T cell populations. How such populations evolve following vacci...

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Detalles Bibliográficos
Autores principales: Bolinger, Beatrice, Sims, Stuart, Swadling, Leo, O’Hara, Geraldine, de Lara, Catherine, Baban, Dilair, Saghal, Natasha, Lee, Lian Ni, Marchi, Emanuele, Davis, Mark, Newell, Evan, Capone, Stefania, Folgori, Antonella, Barnes, Ellie, Klenerman, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670868/
https://www.ncbi.nlm.nih.gov/pubmed/26586434
http://dx.doi.org/10.1016/j.celrep.2015.10.034