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Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks

DNA double-strand breaks (DSBs) elicit the so-called DNA damage response (DDR), largely relying on ataxia telangiectasia mutated (ATM) and DNA-dependent protein kinase (DNA-PKcs), two members of the PI3K-like kinase family, whose respective functions during the sequential steps of the DDR remains co...

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Detalles Bibliográficos
Autores principales: Caron, Pierre, Choudjaye, Jonathan, Clouaire, Thomas, Bugler, Béatrix, Daburon, Virginie, Aguirrebengoa, Marion, Mangeat, Thomas, Iacovoni, Jason S., Álvarez-Quilón, Alejandro, Cortés-Ledesma, Felipe, Legube, Gaëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670905/
https://www.ncbi.nlm.nih.gov/pubmed/26586426
http://dx.doi.org/10.1016/j.celrep.2015.10.024