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MicroRNA-22 inhibits tumor growth and metastasis in gastric cancer by directly targeting MMP14 and Snail

MicroRNAs (miRNAs) deregulation is frequent in human gastric cancers (GCs), but the role of specific miRNAs involved in this disease remains elusive. MiR-22 was previously reported to act as tumor suppressors or oncogenes in diverse cancers. However, their accurate expression, function and mechanism...

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Detalles Bibliográficos
Autores principales: Zuo, Q-F, Cao, L-Y, Yu, T, Gong, L, Wang, L-N, Zhao, Y-L, Xiao, B, Zou, Q-M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670920/
https://www.ncbi.nlm.nih.gov/pubmed/26610210
http://dx.doi.org/10.1038/cddis.2015.297