Cargando…

L-Stepholidine rescues memory deficit and synaptic plasticity in models of Alzheimer's disease via activating dopamine D1 receptor/PKA signaling pathway

It is accepted that amyloid β-derived diffusible ligands (ADDLs) have a prominent role in triggering the early cognitive deficits that constitute Alzheimer's disease (AD). However, there is still no effective treatment for preventing or reversing the progression of the disease. Targeting α-amin...

Descripción completa

Detalles Bibliográficos
Autores principales: Hao, J-R, Sun, N, Lei, L, Li, X-Y, Yao, B, Sun, K, Hu, R, Zhang, X, Shi, X-D, Gao, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670924/
https://www.ncbi.nlm.nih.gov/pubmed/26539912
http://dx.doi.org/10.1038/cddis.2015.315