Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

Inflammasome is an intracellular signaling complex of the innate immune system. Activation of inflammasomes promotes the secretion of interleukin 1β (IL-1β) and IL-18 and triggers pyroptosis. Caspase-1 and -11 (or -4/5 in human) in the canonical and non-canonical inflammasome pathways, respectively,...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Wan-ting, Wan, Haoqiang, Hu, Lichen, Chen, Pengda, Wang, Xin, Huang, Zhe, Yang, Zhang-Hua, Zhong, Chuan-Qi, Han, Jiahuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670995/
https://www.ncbi.nlm.nih.gov/pubmed/26611636
http://dx.doi.org/10.1038/cr.2015.139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670995/
https://www.ncbi.nlm.nih.gov/pubmed/26611636
http://dx.doi.org/10.1038/cr.2015.139

Ejemplares similares