GLUT3 and PKM2 regulate OCT4 expression and support the hypoxic culture of human embryonic stem cells

Human embryonic stem cells (hESCs) have the capacity to differentiate into all cell types and thus have great potential for regenerative medicine. hESCs cultured at low oxygen tensions are more pluripotent and display an increased glycolytic rate but how this is regulated is unknown. This study ther...

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Detalles Bibliográficos
Autores principales: Christensen, David R., Calder, Philip C., Houghton, Franchesca D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671001/
https://www.ncbi.nlm.nih.gov/pubmed/26639784
http://dx.doi.org/10.1038/srep17500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671001/
https://www.ncbi.nlm.nih.gov/pubmed/26639784
http://dx.doi.org/10.1038/srep17500

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