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GLUT3 and PKM2 regulate OCT4 expression and support the hypoxic culture of human embryonic stem cells
Human embryonic stem cells (hESCs) have the capacity to differentiate into all cell types and thus have great potential for regenerative medicine. hESCs cultured at low oxygen tensions are more pluripotent and display an increased glycolytic rate but how this is regulated is unknown. This study ther...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671001/ https://www.ncbi.nlm.nih.gov/pubmed/26639784 http://dx.doi.org/10.1038/srep17500 |