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Detection of gene communities in multi-networks reveals cancer drivers

We propose a new multi-network-based strategy to integrate different layers of genomic information and use them in a coordinate way to identify driving cancer genes. The multi-networks that we consider combine transcription factor co-targeting, microRNA co-targeting, protein-protein interaction and...

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Detalles Bibliográficos
Autores principales: Cantini, Laura, Medico, Enzo, Fortunato, Santo, Caselle, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671005/
https://www.ncbi.nlm.nih.gov/pubmed/26639632
http://dx.doi.org/10.1038/srep17386