Genomic amplification upregulates estrogen-related receptor alpha and its depletion inhibits oral squamous cell carcinoma tumors in vivo

The ESRRA gene encodes a transcription factor and regulates several genes, such as WNT11 and OPN, involved in tumorigenesis. It is upregulated in several cancers, including OSCC. We have previously shown that the tumor suppressor miR-125a targets ESRRA, and its downregulation causes upregulation of...

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Detalles Bibliográficos
Autores principales: Tiwari, Ankana, Swamy, Shivananda, Gopinath, Kodaganur S., Kumar, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671026/
https://www.ncbi.nlm.nih.gov/pubmed/26639757
http://dx.doi.org/10.1038/srep17621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671026/
https://www.ncbi.nlm.nih.gov/pubmed/26639757
http://dx.doi.org/10.1038/srep17621

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