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Molecular Assembly of Clostridium botulinum progenitor M complex of type E

Clostridium botulinum neurotoxin (BoNT) is released as a progenitor complex, in association with a non-toxic-non-hemagglutinin protein (NTNH) and other associated proteins. We have determined the crystal structure of M type Progenitor complex of botulinum neurotoxin E [PTC-E(M)], a heterodimer of Bo...

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Detalles Bibliográficos
Autores principales: Eswaramoorthy, Subramaniam, Sun, Jingchuan, Li, Huilin, Singh, Bal Ram, Swaminathan, Subramanyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671068/
https://www.ncbi.nlm.nih.gov/pubmed/26639353
http://dx.doi.org/10.1038/srep17795