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CD147 monoclonal antibody mediated by chitosan nanoparticles loaded with α-hederin enhances antineoplastic activity and cellular uptake in liver cancer cells

An antibody that specifically interacts with an antigen could be applied to an active targeting delivery system. In this study, CD147 antibody was coupled with α-hed chitosan nanoparticles (α-Hed-CS-NPs). α-Hed-CS-CD147-NPs were round and spherical in shape, with an average particle size of 148.23 ±...

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Detalles Bibliográficos
Autores principales: Zhu, Rong, Zhang, Chun-ge, Liu, Yang, Yuan, Zhi-qiang, Chen, Wei-liang, Yang, Shu-di, Li, Ji-zhao, Zhu, Wen-jing, Zhou, Xiao-feng, You, Ben-gang, Zhang, Xue-nong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671144/
https://www.ncbi.nlm.nih.gov/pubmed/26639052
http://dx.doi.org/10.1038/srep17904