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TNF up-regulates Pentraxin3 expression in human airway smooth muscle cells via JNK and ERK1/2 MAPK pathways

BACKGROUND: Long pentraxin 3 (PTX3) is a novel candidate marker for inflammation in many chronic diseases. As a soluble pattern recognition receptor, PTX3 is involved in amplification of inflammatory reactions and regulation of innate immunity. Previously, we demonstrate that human airway smooth mus...

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Detalles Bibliográficos
Autores principales: Zhang, Jingbo, Koussih, Latifa, Shan, Lianyu, Halayko, Andrew J., Chen, Ben-Kuen, Gounni, Abdelilah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671218/
https://www.ncbi.nlm.nih.gov/pubmed/26644796
http://dx.doi.org/10.1186/s13223-015-0104-y