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Associations of Perfluoroalkyl Substances (PFAS) with Lower Birth Weight: An Evaluation of Potential Confounding by Glomerular Filtration Rate Using a Physiologically Based Pharmacokinetic Model (PBPK)

BACKGROUND: Prenatal exposure to perfluoroalkyl substances (PFAS) has been associated with lower birth weight in epidemiologic studies. This association could be attributable to glomerular filtration rate (GFR), which is related to PFAS concentration and birth weight. OBJECTIVES: We used a physiolog...

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Detalles Bibliográficos
Autores principales: Verner, Marc-André, Loccisano, Anne E., Morken, Nils-Halvdan, Yoon, Miyoung, Wu, Huali, McDougall, Robin, Maisonet, Mildred, Marcus, Michele, Kishi, Reiko, Miyashita, Chihiro, Chen, Mei-Huei, Hsieh, Wu-Shiun, Andersen, Melvin E., Clewell, Harvey J., Longnecker, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671243/
https://www.ncbi.nlm.nih.gov/pubmed/26008903
http://dx.doi.org/10.1289/ehp.1408837