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Re-thinking miRNA-mRNA interactions: Intertwining issues confound target discovery
Despite a library full of literature on miRNA biology, core issues relating to miRNA target detection, biological effect, and mode of action remain controversial. This essay proposes that the predominant mechanism of direct miRNA action is translational inhibition, whereas the bulk of miRNA effects...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley & Sons, Ltd
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671252/ https://www.ncbi.nlm.nih.gov/pubmed/25683051 http://dx.doi.org/10.1002/bies.201400191 |