Evaluation and Validation of Assembling Corrected PacBio Long Reads for Microbial Genome Completion via Hybrid Approaches

Despite the ever-increasing output of next-generation sequencing data along with developing assemblers, dozens to hundreds of gaps still exist in de novo microbial assemblies due to uneven coverage and large genomic repeats. Third-generation single-molecule, real-time (SMRT) sequencing technology av...

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Detalles Bibliográficos
Autores principales: Lin, Hsin-Hung, Liao, Yu-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671558/
https://www.ncbi.nlm.nih.gov/pubmed/26641475
http://dx.doi.org/10.1371/journal.pone.0144305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671558/
https://www.ncbi.nlm.nih.gov/pubmed/26641475
http://dx.doi.org/10.1371/journal.pone.0144305

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