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Exceptional Antibodies Produced by Successive Immunizations

Antibodies stand between us and pathogens. Viruses mutate quickly to avoid detection, and antibodies mutate at similar rates to hunt them down. This death spiral is fueled by specialized proteins and error-prone polymerases that change DNA sequences. Here, we explore how B lymphocytes stay in the ra...

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Detalles Bibliográficos
Autores principales: Gearhart, Patricia J., Castiblanco, Diana P., Russell Knode, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671562/
https://www.ncbi.nlm.nih.gov/pubmed/26641938
http://dx.doi.org/10.1371/journal.pbio.1002321