Gene Delivery by Subconjunctival Injection of Adenovirus in Rats: A Study of Local Distribution, Transgene Duration and Safety

Subconjunctival injection is a minimally invasive route for gene delivery to ocular tissues, but has traditionally been limited to use in the cornea. The accurate ocular distribution of virus has not, however, been previously investigated. Adenovirus is an attractive gene vector as it can deliver la...

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Detalles Bibliográficos
Autores principales: Liu, Guei-Sheung, Wang, Jiang-Hui, Lee, Jia Hui, Tsai, Pei-Jhen, Tsai, Han-En, Sheu, Shwu-Jiuan, Lin, Hsiu-Chen, Dusting, Gregory J., Tai, Ming-Hong, Bee, Youn-Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671571/
https://www.ncbi.nlm.nih.gov/pubmed/26642208
http://dx.doi.org/10.1371/journal.pone.0143956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671571/
https://www.ncbi.nlm.nih.gov/pubmed/26642208
http://dx.doi.org/10.1371/journal.pone.0143956

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