Comparative Genomic Analyses of the Human NPHP1 Locus Reveal Complex Genomic Architecture and Its Regional Evolution in Primates

Many loci in the human genome harbor complex genomic structures that can result in susceptibility to genomic rearrangements leading to various genomic disorders. Nephronophthisis 1 (NPHP1, MIM# 256100) is an autosomal recessive disorder that can be caused by defects of NPHP1; the gene maps within th...

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Detalles Bibliográficos
Autores principales: Yuan, Bo, Liu, Pengfei, Gupta, Aditya, Beck, Christine R., Tejomurtula, Anusha, Campbell, Ian M., Gambin, Tomasz, Simmons, Alexandra D., Withers, Marjorie A., Harris, R. Alan, Rogers, Jeffrey, Schwartz, David C., Lupski, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671654/
https://www.ncbi.nlm.nih.gov/pubmed/26641089
http://dx.doi.org/10.1371/journal.pgen.1005686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671654/
https://www.ncbi.nlm.nih.gov/pubmed/26641089
http://dx.doi.org/10.1371/journal.pgen.1005686

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