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Identification of New Molecular Entities (NMEs) as Potential Leads against Tuberculosis from Open Source Compound Repository

The purpose of this study was to provide a number of diverse and promising early-lead compounds that will feed into the drug discovery pipeline for developing new antitubercular agents. The results from the phenotypic screening of the open-source compound library against Mycobacterium smegmatis and...

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Detalles Bibliográficos
Autores principales: Kotapalli, Sudha Sravanti, Nallam, Sri Satya Anila, Nadella, Lavanya, Banerjee, Tanmay, Rode, Haridas B., Mainkar, Prathama S., Ummanni, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671662/
https://www.ncbi.nlm.nih.gov/pubmed/26642200
http://dx.doi.org/10.1371/journal.pone.0144018