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Developmental Dynamics of X-Chromosome Dosage Compensation by the DCC and H4K20me1 in C. elegans

In Caenorhabditis elegans, the dosage compensation complex (DCC) specifically binds to and represses transcription from both X chromosomes in hermaphrodites. The DCC is composed of an X-specific condensin complex that interacts with several proteins. During embryogenesis, DCC starts localizing to th...

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Detalles Bibliográficos
Autores principales: Kramer, Maxwell, Kranz, Anna-Lena, Su, Amanda, Winterkorn, Lara H., Albritton, Sarah Elizabeth, Ercan, Sevinc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671695/
https://www.ncbi.nlm.nih.gov/pubmed/26641248
http://dx.doi.org/10.1371/journal.pgen.1005698