Physical characterization and in vivo pharmacokinetic study of self-assembling amphotericin B-loaded lecithin-based mixed polymeric micelles

To alleviate the inherent problems of amphotericin B (AmB), such as poor water solubility and nephrotoxicity, a novel self-assembling mixed polymeric micelle delivery system based on lecithin and combined with amphiphilic polymers, Pluronic(®), Kolliphor(®), d-alpha tocopheryl polyethylene glycol su...

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Detalles Bibliográficos
Autores principales: Chen, Ying-Chen, Su, Chia-Yu, Jhan, Hua-Jun, Ho, Hsiu-O, Sheu, Ming-Thau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671761/
https://www.ncbi.nlm.nih.gov/pubmed/26664117
http://dx.doi.org/10.2147/IJN.S95194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671761/
https://www.ncbi.nlm.nih.gov/pubmed/26664117
http://dx.doi.org/10.2147/IJN.S95194

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