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Combination of calcium sulfate and simvastatin-controlled release microspheres enhances bone repair in critical-sized rat calvarial bone defects

Most allogenic bone graft substitutes have only osteoconductive properties. Developing new strategies to improve the osteoinductive activity of bone graft substitutes is both critical and practical for clinical application. Previously, we developed novel simvastatin-encapsulating poly(lactic-co-glyc...

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Detalles Bibliográficos
Autores principales: Fu, Yin-Chih, Wang, Yan-Hsiung, Chen, Chung-Hwan, Wang, Chih-Kuang, Wang, Gwo-Jaw, Ho, Mei-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671780/
https://www.ncbi.nlm.nih.gov/pubmed/26664114
http://dx.doi.org/10.2147/IJN.S88134