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Combination of calcium sulfate and simvastatin-controlled release microspheres enhances bone repair in critical-sized rat calvarial bone defects
Most allogenic bone graft substitutes have only osteoconductive properties. Developing new strategies to improve the osteoinductive activity of bone graft substitutes is both critical and practical for clinical application. Previously, we developed novel simvastatin-encapsulating poly(lactic-co-glyc...
Autores principales: | Fu, Yin-Chih, Wang, Yan-Hsiung, Chen, Chung-Hwan, Wang, Chih-Kuang, Wang, Gwo-Jaw, Ho, Mei-Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671780/ https://www.ncbi.nlm.nih.gov/pubmed/26664114 http://dx.doi.org/10.2147/IJN.S88134 |
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