γ-TEMPy: Simultaneous Fitting of Components in 3D-EM Maps of Their Assembly Using a Genetic Algorithm

We have developed a genetic algorithm for building macromolecular complexes using only a 3D-electron microscopy density map and the atomic structures of the relevant components. For efficient sampling the method uses map feature points calculated by vector quantization. The fitness function combines...

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Detalles Bibliográficos
Autores principales: Pandurangan, Arun Prasad, Vasishtan, Daven, Alber, Frank, Topf, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671957/
https://www.ncbi.nlm.nih.gov/pubmed/26655474
http://dx.doi.org/10.1016/j.str.2015.10.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671957/
https://www.ncbi.nlm.nih.gov/pubmed/26655474
http://dx.doi.org/10.1016/j.str.2015.10.013

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