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Targeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?

Cancer remains a lethal threat to global lives. Development of novel anticancer therapeutics is still a challenge to scientists in the field of biomedicine. In cancer cells, the metabolic features are significantly different from those of normal ones, which are hallmarks of several malignancies. Rec...

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Detalles Bibliográficos
Autores principales: Zhang, Wen, Zhang, Shao-Lin, Hu, Xiaohui, Tam, Kin Yip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671996/
https://www.ncbi.nlm.nih.gov/pubmed/26681918
http://dx.doi.org/10.7150/ijbs.13325