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Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors

Kdm3b is a JmjC domain-containing histone H3 (H3) demethylase and its physiological functions are largely unknown. In this study, we found that Kdm3b protein is highly expressed in multiple cell types in the mouse testes, including Leydig cells, Sertoli cells, spermatogonia and spermatocytes at diff...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoliang, Oyola, Mario G., Zhou, Suoling, Chen, Xian, Liao, Lan, Tien, Jean Ching-Yi, Mani, Shailaja K., Xu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672002/
https://www.ncbi.nlm.nih.gov/pubmed/26681924
http://dx.doi.org/10.7150/ijbs.13795