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Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors
Kdm3b is a JmjC domain-containing histone H3 (H3) demethylase and its physiological functions are largely unknown. In this study, we found that Kdm3b protein is highly expressed in multiple cell types in the mouse testes, including Leydig cells, Sertoli cells, spermatogonia and spermatocytes at diff...
Autores principales: | Liu, Zhaoliang, Oyola, Mario G., Zhou, Suoling, Chen, Xian, Liao, Lan, Tien, Jean Ching-Yi, Mani, Shailaja K., Xu, Jianming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672002/ https://www.ncbi.nlm.nih.gov/pubmed/26681924 http://dx.doi.org/10.7150/ijbs.13795 |
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