Krüppel-Like Factor 5 Promotes Epithelial Proliferation and DNA Damage Repair in the Intestine of Irradiated Mice

BACKGROUND & AIMS: High doses of radiation induce severe DNA damage in intestinal epithelial cells, especially crypt cells, and cause intestinal injury, but the underlying molecular mechanisms remain unclear. Krüppel-like factor 5 (KLF5), a zinc finger-containing transcription factor, is induced...

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Detalles Bibliográficos
Autores principales: Li, Ming, Gu, Yuan, Ma, Yan-Chao, Shang, Zeng-Fu, Wang, Chang, Liu, Fen-Ju, Cao, Jian-Ping, Wan, Hua-Jing, Zhang, Xue-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672003/
https://www.ncbi.nlm.nih.gov/pubmed/26681925
http://dx.doi.org/10.7150/ijbs.13444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672003/
https://www.ncbi.nlm.nih.gov/pubmed/26681925
http://dx.doi.org/10.7150/ijbs.13444

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