Ultrasound Targeted Microbubble Destruction-Mediated Delivery of a Transcription Factor Decoy Inhibits STAT3 Signaling and Tumor Growth

Signal transducer and activator of transcription 3 (STAT3) is constitutively activated in many cancers where it acts to promote tumor progression. A STAT3-specific transcription factor decoy has been developed to suppress STAT3 downstream signaling, but a delivery strategy is needed to improve clini...

Descripción completa

Detalles Bibliográficos
Autores principales: Kopechek, Jonathan A., Carson, Andrew R., McTiernan, Charles F., Chen, Xucai, Hasjim, Bima, Lavery, Linda, Sen, Malabika, Grandis, Jennifer R., Villanueva, Flordeliza S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672019/
https://www.ncbi.nlm.nih.gov/pubmed/26681983
http://dx.doi.org/10.7150/thno.12822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672019/
https://www.ncbi.nlm.nih.gov/pubmed/26681983
http://dx.doi.org/10.7150/thno.12822

Ejemplares similares