Cargando…

Ultrasound Targeted Microbubble Destruction-Mediated Delivery of a Transcription Factor Decoy Inhibits STAT3 Signaling and Tumor Growth

Signal transducer and activator of transcription 3 (STAT3) is constitutively activated in many cancers where it acts to promote tumor progression. A STAT3-specific transcription factor decoy has been developed to suppress STAT3 downstream signaling, but a delivery strategy is needed to improve clini...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kopechek, Jonathan A., Carson, Andrew R., McTiernan, Charles F., Chen, Xucai, Hasjim, Bima, Lavery, Linda, Sen, Malabika, Grandis, Jennifer R., Villanueva, Flordeliza S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672019/ https://www.ncbi.nlm.nih.gov/pubmed/26681983 http://dx.doi.org/10.7150/thno.12822

Ejemplares similares

Cardiac Gene Expression Knockdown Using Small Inhibitory RNA-Loaded Microbubbles and Ultrasound
por: Kopechek, Jonathan A., et al.
Publicado: (2016)

STAT3 decoy oligonucleotide-carrying microbubbles with pulsed ultrasound for enhanced therapeutic effect in head and neck tumors
por: Ramasamy, Thiruganesh, et al.
Publicado: (2020)

Ultrasound and Microbubble-targeted Delivery of a microRNA Inhibitor to the Heart Suppresses Cardiac Hypertrophy and Preserves Cardiac Function
por: Kopechek, Jonathan A., et al.
Publicado: (2019)

Focal areas of increased lipid concentration on the coating of microbubbles during short tone-burst ultrasound insonification
por: Kooiman, Klazina, et al.
Publicado: (2017)

Effect of STAT3 decoy oligodeoxynucleotides mediated by ultrasound-targeted microbubbles combined with ultrasound on the growth of squamous cell carcinoma of the esophagus
por: Zhang, Yan, et al.
Publicado: (2019)

Nucleic acid-based approaches to STAT inhibition
por: Sen, Malabika, et al.
Publicado: (2012)

Augmentation of transgenic expression by ultrasound-mediated liposome microbubble destruction
por: CHEN, ZHI-YI, et al.
Publicado: (2012)

Using ultrasound-targeted microbubble destruction to enhance radiotherapy of glioblastoma
por: Peng, Chanjuan, et al.
Publicado: (2021)

Biochemical Properties of a Decoy Oligodeoxynucleotide Inhibitor of STAT3 Transcription Factor
por: Lee, David S., et al.
Publicado: (2018)

Ultrasound-targeted microbubble destruction for chemotherapeutic drug delivery to solid tumors
por: Chen, Hong, et al.
Publicado: (2013)

Selective depletion of tumor neovasculature by microbubble destruction with appropriate ultrasound pressure
por: Wang, Junfen, et al.
Publicado: (2015)

Ultrasound-mediated microbubble destruction: a new method in cancer immunotherapy
por: Tu, Jiawei, et al.
Publicado: (2018)

Ultrasound Mediated Microbubbles Destruction Augmented Sonolysis: An In Vitro and In Vivo Study
por: Cui, Hai, et al.
Publicado: (2017)

Docetaxel-loaded lipid microbubbles combined with ultrasound-triggered microbubble destruction for targeted tumor therapy in MHCC-H cells
por: Zhang, Yue, et al.
Publicado: (2016)

Effect of Gambogic Acid–Loaded Porous-Lipid/PLGA Microbubbles in Combination With Ultrasound-Triggered Microbubble Destruction on Human Glioma
por: Wang, Feng, et al.
Publicado: (2021)

New Progress in Angiogenesis Therapy of Cardiovascular Disease by Ultrasound Targeted Microbubble Destruction
por: Liao, Yang-Ying, et al.
Publicado: (2014)

Efficient exosome delivery in refractory tissues assisted by ultrasound-targeted microbubble destruction
por: Sun, Wenqi, et al.
Publicado: (2019)

Ultrasound-Targeted Microbubble Destruction: Modulation in the Tumor Microenvironment and Application in Tumor Immunotherapy
por: Han, Ye, et al.
Publicado: (2022)

Use of Nitric Oxide Donor-Loaded Microbubble Destruction by Ultrasound in Thrombus Treatment
por: Corro, Ricardo, et al.
Publicado: (2022)

Ultrasound-targeted microbubble destruction remodels tumour microenvironment to improve immunotherapeutic effect
por: Liu, Senbo, et al.
Publicado: (2022)

Ultrasound microbubble-mediated transfection of NF-κB decoy oligodeoxynucleotide into gingival tissues inhibits periodontitis in rats in vivo
por: Yamaguchi, Hiroyuki, et al.
Publicado: (2017)

A new approach to transfect NF-κB decoy oligodeoxynucleotides into the periodontal tissue using the ultrasound-microbubble method
por: Yamaguchi, Hiroyuki, et al.
Publicado: (2017)

Ultrasound with microbubbles
por: Harvey, Chris
Publicado: (2015)

Ultrasound Targeted Microbubble Destruction Stimulates Cellular Endocytosis in Facilitation of Adeno-Associated Virus Delivery
por: Jin, Li-Fang, et al.
Publicado: (2013)

Unilateral Opening of Rat Blood-Brain Barrier Assisted by Diagnostic Ultrasound Targeted Microbubbles Destruction
por: Xu, Yali, et al.
Publicado: (2016)

Delivery of Hydrogen Sulfide by Ultrasound Targeted Microbubble Destruction Attenuates Myocardial Ischemia-reperfusion Injury
por: Chen, Gangbin, et al.
Publicado: (2016)

Ultrasound-targeted microbubble destruction in gene therapy: A new tool to cure human diseases
por: Wu, Jun, et al.
Publicado: (2016)

Ultrasound-targeted microbubble destruction-mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer
por: Cheng, Li, et al.
Publicado: (2021)

Ultrasound-Induced Destruction of Nitric Oxide–Loaded Microbubbles in the Treatment of Thrombus and Ischemia–Reperfusion Injury
por: Liang, Zenghui, et al.
Publicado: (2022)

STAT3 Oligonucleotide Inhibits Tumor Angiogenesis in Preclinical Models of Squamous Cell Carcinoma
por: Klein, Jonah D., et al.
Publicado: (2014)

Ultrasound targeted microbubble destruction-triggered nitric oxide release via nanoscale ultrasound contrast agent for sensitizing chemoimmunotherapy
por: Zhao, Yading, et al.
Publicado: (2023)

EGFP gene transfection into the synovial joint tissues of rats with rheumatoid arthritis by ultrasound-mediated microbubble destruction
por: JING, XIANG-XIANG, et al.
Publicado: (2014)

Nanoparticles Formed by Acoustic Destruction of Microbubbles and Their Utilization for Imaging and Effects on Therapy by High Intensity Focused Ultrasound
por: Blum, Nicholas T., et al.
Publicado: (2017)

Ultrasound-targeted microbubble destruction promotes myocardial angiogenesis and functional improvements in rat model of diabetic cardiomyopathy
por: Zhang, Xijun, et al.
Publicado: (2021)

Ultrasound-Targeted Microbubble Destruction-Mediated Inhibition of Livin Expression Accelerates Ovarian Cancer Cell Apoptosis
por: Xu, Xiaolin, et al.
Publicado: (2021)

Ultrasound‐targeted microbubble destruction mediates PDE5i/NO integration for cavernosum remodeling and penile rehabilitation
por: Yang, Wende, et al.
Publicado: (2023)

Nonspherical ultrasound microbubbles
por: Dasgupta, Anshuman, et al.
Publicado: (2023)

Ultrasound-targeted microbubble destruction mediated herpes simplex virus-thymidine kinase gene treats hepatoma in mice
por: Zhou, Shiji, et al.
Publicado: (2010)

Enhancement of Angiogenesis by Ultrasound-Targeted Microbubble Destruction Combined with Nuclear Localization Signaling Peptides in Canine Myocardial Infarction
por: Cui, Jingjing, et al.
Publicado: (2017)

Ultrasound-targeted microbubble destruction-mediated miR-205 enhances cisplatin cytotoxicity in prostate cancer cells
por: Qin, Dingwen, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_i3bf4a2mcgvap03ba830j31l9u