Generation of Functional Neuromuscular Junctions from Human Pluripotent Stem Cell Lines

Several neuromuscular diseases involve dysfunction of neuromuscular junctions (NMJs), yet there are no patient-specific human models for electrophysiological characterization of NMJ. We seeded cells of neurally-induced embryoid body-like spheres derived from induced pluripotent stem cell (iPSC) or e...

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Detalles Bibliográficos
Autores principales: Puttonen, Katja A., Ruponen, Marika, Naumenko, Nikolay, Hovatta, Outi H., Tavi, Pasi, Koistinaho, Jari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672046/
https://www.ncbi.nlm.nih.gov/pubmed/26696831
http://dx.doi.org/10.3389/fncel.2015.00473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672046/
https://www.ncbi.nlm.nih.gov/pubmed/26696831
http://dx.doi.org/10.3389/fncel.2015.00473

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