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Detection of a PDGFRB fusion in refractory CMML without eosinophilia: A case for broad spectrum tumor profiling

In this case report, we describe a refractory CMML case without eosinophilia harboring a PDGFRB rearrangement leading to a favorable response with imatinib. We believe this case demonstrates the utility of broad spectrum genomic profiling in refractory CMML cases as an opportunity to uncover additio...

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Detalles Bibliográficos
Autores principales: Bell, Gillian C., Padron, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672079/
https://www.ncbi.nlm.nih.gov/pubmed/26716078
http://dx.doi.org/10.1016/j.lrr.2015.07.002