Cargando…
Detection of a PDGFRB fusion in refractory CMML without eosinophilia: A case for broad spectrum tumor profiling
In this case report, we describe a refractory CMML case without eosinophilia harboring a PDGFRB rearrangement leading to a favorable response with imatinib. We believe this case demonstrates the utility of broad spectrum genomic profiling in refractory CMML cases as an opportunity to uncover additio...
Autores principales: | Bell, Gillian C., Padron, Eric |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672079/ https://www.ncbi.nlm.nih.gov/pubmed/26716078 http://dx.doi.org/10.1016/j.lrr.2015.07.002 |
Ejemplares similares
-
Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions
por: Valent, Peter, et al.
Publicado: (2019) -
NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors
por: Byrgazov, K, et al.
Publicado: (2017) -
Cytogenetically cryptic ZMYM2-FLT3 and DIAPH1-PDGFRB gene fusions in myeloid neoplasms with eosinophilia
por: Jawhar, Mohamad, et al.
Publicado: (2017) -
Identification of a Novel
CSNK2A1-PDGFRB Fusion Gene in a Patient
with Myeloid Neoplasm with Eosinophilia
por: Xu, Xiaoyu, et al.
Publicado: (2021) -
Outcomes and molecular profile of oligomonocytic CMML support its consideration as the first stage in the CMML continuum
por: Calvo, Xavier, et al.
Publicado: (2022)