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CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure

BACKGROUND & AIMS: Liver regeneration requires functional liver macrophages, which provide an immune barrier that is compromised after liver injury. The numbers of liver macrophages are controlled by macrophage colony-stimulating factor (CSF1). We examined the prognostic significance of the seru...

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Detalles Bibliográficos
Autores principales: Stutchfield, Benjamin M., Antoine, Daniel J., Mackinnon, Alison C., Gow, Deborah J., Bain, Calum C., Hawley, Catherine A., Hughes, Michael J., Francis, Benjamin, Wojtacha, Davina, Man, Tak Y., Dear, James W., Devey, Luke R., Mowat, Alan M., Pollard, Jeffrey W., Park, B. Kevin, Jenkins, Stephen J., Simpson, Kenneth J., Hume, David A., Wigmore, Stephen J., Forbes, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672154/
https://www.ncbi.nlm.nih.gov/pubmed/26344055
http://dx.doi.org/10.1053/j.gastro.2015.08.053