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CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure
BACKGROUND & AIMS: Liver regeneration requires functional liver macrophages, which provide an immune barrier that is compromised after liver injury. The numbers of liver macrophages are controlled by macrophage colony-stimulating factor (CSF1). We examined the prognostic significance of the seru...
Autores principales: | Stutchfield, Benjamin M., Antoine, Daniel J., Mackinnon, Alison C., Gow, Deborah J., Bain, Calum C., Hawley, Catherine A., Hughes, Michael J., Francis, Benjamin, Wojtacha, Davina, Man, Tak Y., Dear, James W., Devey, Luke R., Mowat, Alan M., Pollard, Jeffrey W., Park, B. Kevin, Jenkins, Stephen J., Simpson, Kenneth J., Hume, David A., Wigmore, Stephen J., Forbes, Stuart J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
W.B. Saunders
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672154/ https://www.ncbi.nlm.nih.gov/pubmed/26344055 http://dx.doi.org/10.1053/j.gastro.2015.08.053 |
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