Cargando…

Depolarization of Hippocampal Neurons Induces Formation of Nonsynaptic NMDA Receptor Islands Resembling Nascent Postsynaptic Densities123

Depolarization of neurons in 3-week-old rat hippocampal cultures promotes a rapid increase in the density of surface NMDA receptors (NRs), accompanied by transient formation of nonsynaptic NMDA receptor clusters or NR islands. Islands exhibit cytoplasmic dense material resembling that at postsynapti...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao-Cheng, Jung-Hwa, Azzam, Rita, Crocker, Virginia, Winters, Christine A., Reese, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672205/
https://www.ncbi.nlm.nih.gov/pubmed/26665164
http://dx.doi.org/10.1523/ENEURO.0066-15.2015