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Depolarization of Hippocampal Neurons Induces Formation of Nonsynaptic NMDA Receptor Islands Resembling Nascent Postsynaptic Densities123
Depolarization of neurons in 3-week-old rat hippocampal cultures promotes a rapid increase in the density of surface NMDA receptors (NRs), accompanied by transient formation of nonsynaptic NMDA receptor clusters or NR islands. Islands exhibit cytoplasmic dense material resembling that at postsynapti...
Autores principales: | Tao-Cheng, Jung-Hwa, Azzam, Rita, Crocker, Virginia, Winters, Christine A., Reese, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672205/ https://www.ncbi.nlm.nih.gov/pubmed/26665164 http://dx.doi.org/10.1523/ENEURO.0066-15.2015 |
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