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Association of BRCA1 promoter methylation with sporadic breast cancers: Evidence from 40 studies
Breast cancer susceptibility gene 1 (BRCA1) located at chromosome 17q12-21 is a classic tumor suppressor gene, and has been considered as a significant role in hereditary breast cancers. Moreover, numerous studies demonstrated the methylation status of CpG islands in the promoter regions of BRCA1 ge...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672329/ https://www.ncbi.nlm.nih.gov/pubmed/26643130 http://dx.doi.org/10.1038/srep17869 |