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The hematopoietic regulator, ELF-1, enhances the transcriptional response to Interferon-β of the OAS1 anti-viral gene

Interferon (IFN) therapy is effective in treating cancers, haematological and virus induced diseases. The classical Jak/Stat pathway of IFN signal transduction leading to changes in transcriptional activity is well established but alone does not explain the whole spectrum of cellular responses to IF...

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Detalles Bibliográficos
Autores principales: Larsen, Steven, Kawamoto, Shota, Tanuma, Sei-ichi, Uchiumi, Fumiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672336/
https://www.ncbi.nlm.nih.gov/pubmed/26643049
http://dx.doi.org/10.1038/srep17497