Drug-Drug Interaction Potentials of Tyrosine Kinase Inhibitors via Inhibition of UDP-Glucuronosyltransferases

Tyrosine kinase inhibitors (TKIs) are anticancer drugs that may be co-administered with other drugs. The aims of this study are to investigate the inhibitory effects of TKIs on UDP-glucuronosyltransferase (UGT) activities, and to quantitatively evaluate their potential to cause drug-drug interaction...

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Detalles Bibliográficos
Autores principales: Zhang, Nan, Liu, Yong, Jeong, Hyunyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672351/
https://www.ncbi.nlm.nih.gov/pubmed/26642944
http://dx.doi.org/10.1038/srep17778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672351/
https://www.ncbi.nlm.nih.gov/pubmed/26642944
http://dx.doi.org/10.1038/srep17778

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