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Distribution of mutational fitness effects and of epistasis in the 5’ untranslated region of a plant RNA virus
BACKGROUND: Understanding the causes and consequences of phenotypic variability is a central topic of evolutionary biology. Mutations within non-coding cis-regulatory regions are thought to be of major effect since they affect the expression of downstream genes. To address the evolutionary potential...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672503/ https://www.ncbi.nlm.nih.gov/pubmed/26643527 http://dx.doi.org/10.1186/s12862-015-0555-2 |