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Distribution of mutational fitness effects and of epistasis in the 5’ untranslated region of a plant RNA virus

BACKGROUND: Understanding the causes and consequences of phenotypic variability is a central topic of evolutionary biology. Mutations within non-coding cis-regulatory regions are thought to be of major effect since they affect the expression of downstream genes. To address the evolutionary potential...

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Detalles Bibliográficos
Autores principales:	Bernet, Guillermo P., Elena, Santiago F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672503/ https://www.ncbi.nlm.nih.gov/pubmed/26643527 http://dx.doi.org/10.1186/s12862-015-0555-2

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