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Haemophilus influenzae induces steroid-resistant inflammatory responses in COPD

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder partially resistant to glucocorticoids. A reduced histone deacetylase (HDAC) activity has been proposed to explain this resistance. Haemophilus influenzae frequently colonizes the airways of COPD patients, where it...

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Detalles Bibliográficos
Autores principales: Cosío, Borja G., Jahn, Andreas, Iglesias, Amanda, Shafiek, Hanaa, Busquets, Xavier, Agustí, Alvar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672509/
https://www.ncbi.nlm.nih.gov/pubmed/26642881
http://dx.doi.org/10.1186/s12890-015-0155-3