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High-grade serous ovarian cancer cell lines exhibit heterogeneous responses to growth factor stimulation

BACKGROUND: The factors driving the onset and progression of ovarian cancer are not well understood. Recent reports have identified cell lines that are representative of the genomic pattern of high-grade serous ovarian cancer (HGSOC), in which greater than 90 % of tumors have a mutation in TP53. How...

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Detalles Bibliográficos
Autores principales: Bourgeois, Danielle L., Kabarowski, Karl A., Porubsky, Veronica L., Kreeger, Pamela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672525/
https://www.ncbi.nlm.nih.gov/pubmed/26648788
http://dx.doi.org/10.1186/s12935-015-0263-4