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High-grade serous ovarian cancer cell lines exhibit heterogeneous responses to growth factor stimulation
BACKGROUND: The factors driving the onset and progression of ovarian cancer are not well understood. Recent reports have identified cell lines that are representative of the genomic pattern of high-grade serous ovarian cancer (HGSOC), in which greater than 90 % of tumors have a mutation in TP53. How...
Autores principales: | Bourgeois, Danielle L., Kabarowski, Karl A., Porubsky, Veronica L., Kreeger, Pamela K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672525/ https://www.ncbi.nlm.nih.gov/pubmed/26648788 http://dx.doi.org/10.1186/s12935-015-0263-4 |
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